March 2024 Patent Highlights | drughunters.com/3JZWYbH

Our team at Drug Hunter has compiled a annotated, searchable table including information from more than 200 patents from March 2024 of potential interest to drug hunters, along with highlights from some of our favorites.

M4205 (IDRX-42): A Selective KIT Inhibitor With a Non-Classical Hinge Binder for the Treatment of Gastrointestinal Stromal Tumors

This article highlights the discovery, strategies for de-risking hERG liabilities, and preliminary clinical data.

Article | drughunters.com/3JKdhZL

📢 Register Now! bit.ly/drughunters
A fantastic programme of speakers from across industry and academia, with topics ranging from cheminformatics and model building to computational-driven drug design and structural understanding.

📢 Register Now! bit.ly/drughunters
This event is intended for any drug hunters in academia or industry who would like to expand their understanding of computational techniques and learn more about how computational chemistry is applied in drug discovery.

March 2024 Molecule Roundup: PARP1, TNIK, and MKK4 Inhibitors, mGluR5 Modulator, and More

Here we curated a table of nearly 70 molecules that caught our interest from March 2024, along with highlights from some of our favorites!

Article Link | drughunters.com/3UPG4ml

Sage Therapeutics/Biogen Secure FDA Approval for Zuranolone (ZURZUVAE) as the First Oral Treatment for Postpartum Depression | drughunters.com/3UQdbX5

In Aug 2023, the FDA approved zuranolone (ZURZUVAE™), Sage Therapeutics/Biogen’s oral postpartum depression drug.

DCC-3116: Deciphera Unveils a First-in-Class Oral ULK1/2 Autophagy Inhibitor with Broad Combination Potential | drughunters.com/3wb8NrY

Deciphera’s ULK1/2 inhibitor, targeting autophagy, was disclosed at the ACS Spring 2024 meeting and included preclinical combination data.

PRMT5 Target Review: The Next ‘First-in-Class’ Epigenetic Drug | drughunters.com/3JWq2AO

Learn more about PRMT5, the currently available data for compounds in clinical trials, how they differentiate, and what’s next in the field of PRMT5 inhibitors.

A Guide to Generative AI for Medicinal Chemists | drughunters.com/3JSMTNq

Thursday, May 23
8:00am PDT // 11:00 am EDT // 5:00 pm CEST

In this Flash Talk, Ashwini Ghogare explores how Medicinal Chemists can benefit from Using Generative AI.

#drughunter

Molecules of the Month – April 2024

Find out what compounds made our April 2024 Molecules of the Month list and check out recent articles for each.

Article | drughunters.com/3wD1WYB

Fremtidens life science-talenter!
Lundbeck afholder #Drughunters og samler 200 knivskarpe gymnasieelever til konkurrence og jagt på det næste store medicinfremskridt. Selvfølgelig med et stærkt hold fra mit gymnasium, Viborg Gymnasium 💪🇩🇰 #dkpol Lundbeckfonden

Blueprint’s Selective CDK2 Inhibitor

Learn about the discovery story, how exquisite kinome selectivity can be achieved, interim clinical data, and more in this full case study about BLU-222.

Article | drughunters.com/4dAgCs5

Schrödinger’s MALT1 Inhibitor Showcases the Potential of Its Computational Platform and Becomes Its First In-House Clinical Compound | drughunters.com/3Qu5B1z

SGR-1505, the first in-house clinical compound developed at Schrodinger is an oral, allosteric MALT1 inhibitor.

Чат-бот DrugHunters у дії: патрульні виявили у вінничанина, ймовірно, наркотичні речовини.
Подробиці: facebook.com/vinnytsiapolic…

AstraZeneca’s Oral, Selective CDK2 Inhibitor for the Treatment of CDK4/6-Inhibitor Resistant Cancers and CCNE1-Amplified Tumors | drughunters.com/3V3koTB

Read our case study on AZ’s newly disclosed CDK2-selective clinical compound, AZD8421.

Medicxi launch the fourth edition of its venture fund for biopharma entrepreneurs

healthcaremea.com/medicxi-launch…

#uk #europe #biopharma #drughunters #medicxiiv #pharmaceuticalindustry #commercialandtechnicalsupport #assetcentricinvestmentmodel

Поліція продовжує знаходити у кременчужан наркотики

Патрульні продовжують виявляти у громадян наркотичні речовини. Поліція нагадує, що в месенджері Telegram працює офіційний чат-бот від патрульної поліції DrugHunters, який допомагає викривати збут наркот kremen.today/2023/08/27/pol…

Нагадуємо, що працює чат-бот DrugHunters t.me/drughunters_uk…, який допомагає викривати збут наркотиків.

Деталі: m.facebook.com/story.php?stor…

Drug Discovery News Roundup from April 2024

In case you missed anything, here’s a recap of the most notable drug discovery news highlights from April 2024!

Link | drughunters.com/4bttIFF

TODAY: Meet Our Team | drughunters.com/3V6hUUJ

Join us for a coffee chat this morning to meet scientists at Drug Hunter, hear what the team is excited about in drug discovery, and get a chance to ask them questions!

Friday, May 17
9:00am PDT/12:00 am EDT/6:00 pm CEST