This study into the role of PDCD4 in the pathogenesis of premature ovarian insufficiency adds to our understanding of the formation of POI and potential therapeutic interventions.

doi.org/10.1016/j.rbmo…

This work from Hongshan Ge and team at Jiangsu Taizhou People's Hospital provides insights into the mechanisms underlying hyperandrogenism-induced dysfunction of GCs in PCOS.

The paper is published open access, available now from our in-press articles

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In this study from Nick Macklon and colleagues, double blastocyst vitrification and warming did not compromise embryos either in terms of their quality or potential to establish and maintain pregnancy.

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This Commentary article from Sandro Esteves and Peter Humaidan provides insight and several compelling reasons as to why we should give male infertility a prime time space in our attention.

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Volume 48, Issue 5 of RBMO is out now!

15 original research papers & review articles, plus a new Canadian Fertility & Andrology Society Canadian Fertility and Andrology Society clinical practice guideline - Fertility preservation in patients undergoing gonadotoxic treatments

rbmojournal.com/issue/S1472648…

This new study into intra-abdominal fat obesity and female reproductive health indicates that enlarged visceral adipose tissue area was associated with an increased risk of infertility.

doi.org/10.1016/j.rbmo…

Defining quality of peer review and how that quality should be measured is difficult - Please share your thoughts on this topic by responding to EASE RFI - forms.gle/CogPWXdxVsexQv…

This new review in our June issue is the first retrospective analyses of follicular fluid metabolomic profiling to understand infertility diseases as oocytes development for IVF, and reflects on workflows to obtain robust data in future.

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In contrast to the findings of a recent systematic review showing vitamin D deficiency had a significantly increased risk of miscarriage, this retrospective analysis of 371 women found no risk to pregnancy in women with lower levels of vitamin D

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Have you weighed in on this year's #PeerReviewWeek theme? The options are:

- Innovation and Technology
- DEIA
- Ethical Integrity
- Optimizing the Research Experience

Cast your vote: bit.ly/prwtheme24

#PeerReviewWeek

A new study confirms that application of a single micro-dose of copper chloride gel to the endometrium of healthy volunteers results in an increase in endometrial growth and VEGF production without adverse impact on endometrial or embryo development.

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Nice illustrative depiction of the protocol used in the article 'Modified natural cycle allows a window of 7 days for frozen embryo transfer planning'

sciencedirect.com/science/articl…

It’s Sunday morning – time to catch up with the highlights from the past few months, in the Spring 2024 edition of RBMO Digest.

Read on for:

🔥Hot Topics
👨‍⚖️Editor’s Choice
📄Review articles
🧑‍🔬Countercurrent contributions
🔖 and an RTS Section Profile

sciencedirect.com/journal/reprod…

This new systematic review and meta-analysis from Sonia Gayete-Lafuente and team, provides a comprehensive perspective on the relationship between ovarian endometriomas (OMA) and IVF outcomes.

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This study demonstrates that the addition of adipose tissue-derived stem cell-conditioned medium (ASC-CM) to bovine ovarian tissue IVC medium enhances follicle survival, development and oestradiol secretion, and promotes the viability of stromal cells.

doi.org/10.1016/j.rbmo…

The Spring 2024 edition of our regular Digest of news and highlights is out now.

With choice picks of recent papers by Chief Editors Nick Macklon and Juancho G. Velasco, Hot Topics selected by Editors Richard A Anderson & Mina Alikani and more!

sciencedirect.com/journal/reprod…

We are looking forward to it!

Huge congratulations again to our RGE Prize winners.

Read the full announcement, the winning paper and two runners up on our website

sciencedirect.com/journal/reprod…

This study from Ruth Shalgi and team at Tel-Aviv University investigates the involvement of pigment epithelium-derived factorin folliculogenesis, focusing on the interrelationships between PEDF and the well-described factors of FSH and AMH

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Embryo blastomeres and the zona pellucida are occasionally damaged during vitrification.

This new paper investigates whether this results from crack-induced mechanical damage in the glass state, caused by external bending of the device.

doi.org/10.1016/j.rbmo…